DRIVING DISCOVERY ACHIEVING BREAKTHROUGHS

 

Our passion is improving health. That is what keeps us at the forefront of scientific discovery and development.

Behind each of our medicines and vaccines is a team of researchers who are leaders in their fields. People whose unwavering enthusiasm for finding new ways to prevent and treat disease is matched only by their unrelenting commitment to scientific excellence and patient safety. 

We are entering an exciting period with a strong product pipeline that targets a broad range of diseases. And we're looking ahead to the next generation of healthcare by using new techniques and technologies.


Therapeutic Areas:

We focus our research on several key therapeutic areas, including: 

• Diabetes and Obesity
• Bone diseases and Immunology
• Infectious disease and Antibiotic resistance
• Oncology
• Vaccines and Immunoprophylaxis
• Animal health 

PIPELINE 

From preclinical development to Phase III clinical trials, our passion for advancing health through science is evident in the breadth and depth of our pipeline.

Explore our pipeline. Please visit Corporate Headquarters Site.

DISCOVERY AND DEVELOPMENT 

Bringing important medicines and vaccines to people around the world through breakthrough science. This is the heart of what we do. 

Novel medicines 

Vaccines to help prevent disease. The work we do in our labs has helped to save and improve countless lives. Thanks to our world-class researchers, state-of-the-art technologies and unrelenting focus on scientific excellence, MSD is at the forefront of discovering and developing new ways to treat and prevent disease. 

Scientific discovery and development have always been the cornerstones of our company. Today, we conduct research in a broad range of therapeutic categories – including cardiovascular disease, infectious diseases, vaccines, cancer, neurology and women’s health. And, to help achieve our goal of saving and improving lives around the world, we are expanding our capabilities in new areas, such as biologics. 

Did You Know? 

The process of drug discovery and development is long and challenging. It begins by first exploring the roots of a disease or condition. If a compound proves promising, it then continues through years of testing and has to obtain regulatory approval before it reaches the market. A very small fraction of the compounds that commence evaluation will ultimately survive the tough process of research, development and testing to finally become medicines. 

PUTTING RESEARCH AND DEVELOPMENT TO WORK 

See how the work we do in our labs can make a real difference in people’s lives. 

CLINICAL TRIALS 

Looking for information about MSD-sponsored clinical trials? MSD posts information online about MSD-sponsored clinical trials in patients – including the results of those trials, regardless of outcome. 

Learn more

CLINICAL DEVELOPMENT 

People count on us to make medicines and vaccines that have well documented safety and effectiveness profiles and offer value. Clinical trials (also known as clinical studies) are a critical step in this process. 

Before they may receive approval for use, medicine and vaccine candidates undergo rigorous and systematic testing in volunteers. This process is designed to evaluate whether a new product should be approved for use in the broader population. 

Each clinical trial is designed to answer certain research questions. They follow strict, predefined protocols to ensure safe and accurate results. Each phase has a different purpose in the development of a medicine or vaccine: 

• Phase I: Researchers test an experimental drug or treatment in a small group of healthy volunteers (20-80) for the first time to evaluate its safety and trace what happens to the compound in the body.
• Phase II: The drug or treatment being studied is given to a larger group of people with the disease (100-300) to obtain preliminary evidence of an effect, to determine the dosage and route of administration, and to further evaluate its safety. If there is evidence of an effect and the risks are considered acceptable, the drug may move to the next stage.
• Phase III: This phase of trial tests the drug candidate in a larger number of people with the disease (1,000-3,000), further testing its effectiveness and safety. In some cases this will be compared to a treatment standard, if one is already available.
• Phase IV: After a drug or treatment has been approved by the appropriate government and regulatory agencies and is being marketed, we may study its safety and effectiveness over a longer period of time and in a larger number of people. We may also continue to study some of our marketed products for new indications. Thousands of people usually participate in Phase IV trials. 

At MSD, our clinical trials are designed, conducted and monitored in adherence to the same standards, whether they take place in the United States or elsewhere around the world. In conducting clinical trials, we also adhere to the guidelines of The International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use. 

Interested in Participating in One of Our Clinical Trials? 

MSD-sponsored clinical trials in patients are registered on ClinicalTrials.gov, a service of the U.S. National Institutes of Health. Information about ongoing clinical trials is also available online through the International Federation of Pharmaceutical Manufacturers & Associations (IFPMA). 

Note: MSD and Schering-Plough have combined our global operations under the name Merck & Co., Inc., Kenilworth, NJ, USA.. We are working to update our entries in these two online registries to reflect this change. In the meantime, you can search for information about our ongoing clinical trials by using both "MSD" and "Schering-Plough" as search terms. 

Results of MSD-sponsored Clinical Trials 

We are committed to the timely registration of clinical trials in patients and disclosure of those clinical trial results regardless of their outcome. We seek to provide balanced and accurate information about our studies, and have strict guidelines in place to guide publication. We also disclose medically important safety data from other studies. In addition to publishing our clinical trial results in peer-reviewed medical journals, we post study results of our marketed products on ClinicalTrials.gov. 

MSD Policies and Perspectives 

Clinical Trial Registries and the Publication of Clinical Trial Results